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Peptidylglycine alpha-amidating monooxygenase antibody mediated.

Overexpression of membrane PAM in corticotrope tumor cells reorganizes the actin cytoskeleton, shifts endogenous adrenocorticotropic hormone ACTH from mature granules localized at the tips of processes to the TGN region, and blocks regulated secretion. AtT corticotrope tumor cells have...

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Peptidylglycine alpha-amidating monooxygenase antibody mediated

   23.02.2020  6 Comments
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Systems used to automatically annotate proteins with high accuracy:. Select item s and click on "Add to basket" to create your own collection here entries max. Manual assertion based on experiment...

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Peptidylglycine alpha-amidating monooxygenase antibody mediated

MAUDE 23.02.2020 6 Comments

Results: Modification-specific antibodies reveal that peptide substrate amidation is strikingly sensitive to the exposure of cells to moderate hypoxia. Conclusion: PAM-dependent amidation has the potential to signal oxygen levels in the...

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This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase PHM...

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Search for more papers by this author. E-mail Address: eipper uchc. Overexpression of membrane PAM in corticotrope tumor cells reorganizes the actin cytoskeleton, shifts endogenous adrenocorticotropic hormone ACTH from mature...

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Interactions between biological pathways and molecular oxygen require robust mechanisms for detecting and responding to changes in cellular oxygen availability, to support oxygen homeostasis. Here we show that Peptidylglycine alpha-amidating monooxygenase antibody...

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Entry whose protein s existence is based on evidence at protein level. Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl 2-hydroxyglycine intermediate that is dismutated to glyoxylate...

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6 thoughts on “Peptidylglycine alpha-amidating monooxygenase antibody mediated

  1. PHMcc partially co-migrated with a Golgi marker during subcellular fractionation and partially co-localized with Ccc2 based on immunofluorescence.

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